Biological and Translational Cancer Research
Research Topic
Anti-oxidants and Innovative Natural Products
Oxidative stress is an imbalance between free radicals and anti-oxidant capacity. It has been proposed to play an important role in the progression of pathological changes including cancer, aging, and hyperpigmentation.
We emphasize on the research field of innovative natural products to prevent pathological changes of cancer, aging, and hyperpigmentation.
- Scopes of the research:
– Innovative Natural Products
– Free radicals and Anti-oxidants
– Oxidative Stress and Patho-mechanisms; Cancer, Aging, Hyperpigmentation
Prasit Suwannalert, Ph.D
Dean, Associate Professor
Witchuda Payuhakrit, Ph.D
Assistant Professor
Research Topic
Tumor microenvironment and Anti-aging research
The research focuses on the tumor microenvironment, exploring how cellular interactions and stromal cells influence cancer progression and therapy. It also conducts anti-aging and age-related disease research, studying molecular mechanisms such as cellular senescence and oxidative stress to identify potential interventions. Additionally, the research includes natural product research and development, aiming to discover bioactive compounds for therapeutic applications. Furthermore, it focuses on histological techniques and histopathology, supporting detailed tissue analysis for disease pathology and translational research.
- Scopes of the research:
– Tumor microenvironment
– Anti-aging and age-related diseases research
– Natural product research and development
– Histological techniques and histopathology
Research Topic
Hypoxia and cancer biology
Cancer microenvironment plays a crucial role in progression, aggressiveness and resistance to treatment in many types of cancer. Specifically, hypoxic microenvironment (low oxygenation) due to fast tumor growth exceeding rate of new blood vessel formation can activate various molecular pathways involved with carcinogenesis and drug resistance. Our laboratory aims to study various responses to hypoxic activation and the molecular pathways involved to ultimately develop novel treatment strategies for cancer.
- Scopes of the research:
– Hypoxia-induced drug resistance
– Hypoxia-induced microparticles
– Hypoxia-induced cancer stem cells
Titipatima Sakulterdkiat, M.D., Ph.D
Lecturer
Chonnapat Naktubtim
Assistant Instructor
Research Topic
Cancer Biology and In Silico Analysis
Our research explores the molecular mechanisms underlying cancer and utilizes in silico methods to identify potential therapeutic targets. By integrating bioinformatics and protein interaction networks to analyze signaling pathways and tumor microenvironments, this study supports the development of multi-target treatments for cancer.
- Scopes of the research:
– Molecular and Cellular Mechanisms of Cancer
– Network-Based Target Identification
Research Topic
Pathobiology of Gastrointestinal diseases
Gastrointestinal (GI) diseases represent a significant global health burden, affecting millions of people and crucial economic animals each year. These diseases encompass a wide spectrum of conditions, including inflammatory bowel disease (IBD), infections, metabolic disorders, and cancers of the digestive tract. Understanding the mechanisms underlying these disorders is essential for the development of effective diagnostics, treatments, and prevention strategies.
- Scopes of the research:
– Gastrointestinal biology and pathology
– Gastrointestinal organoid development
– Gastrointestinal cancers
– Zebrafish model for pathobiology
Tharathip Muangthong, Ph.D
Senior Researcher