Prasit Suwannalert, Ph.D
Associate Professor
E-mail: prasit.suw@mahidol.ac.th
Tel:
Research Topics & Interests
Topic
Free radicals and pathological changes
RATIONAL AND RESEARCH METHODOLOGY : An imbalance between radicals and anti-radicals capacity has been proposed to play an important role in the progression of pathological changes. Oxidative stress is considered a major contributor to various pathologies including aging and cancers. The research is on the field of antioxidants and natural products prevent pathological changes of aging and cancers.
Scope of Research
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- Anti-oxidants of natural products
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- Oxidative stress and cancer
- Anti-melanogenesis
Publication / Presentation
Publication
- 17-AAG Induces Endoplasmic Reticulum Stress-mediated Apoptosis in Breast Cancer Cells, Possibly Through PERK/eIF2α Up-regulation
In Vivo / 1 September 2024
- Skin anti-aging and wound healing effects of a passion fruit seed extract rich in piceatannol
Nutrition and Healthy Aging / 25 July 2024
- A Potential Combination of Targeting HSP90 and mTOR in Breast Cancer Cell Growth, Migration, and Invasion Through Inhibiting AKT Phosphorylation and F-actin Organization
Anticancer Research / June 2024
- Piceatannol-rich extract from Passiflora edulis Sims seeds attenuates morphological differentiation through the reduction of MITF mRNA expression and F-actin polymerization in UVB-induced hyperpigmented B16F10 cells
Journal of Pharmacy and Pharmacognosy Research / 2024
- RED RICE BRAN EXTRACT SUPPRESSES COLON CANCER CELLS VIA APOPTOSIS INDUCTION/CELL CYCLE ARREST AND EXERTS ANTIMUTAGENIC ACTIVITY
Experimental Oncology / 14 October 2023
- Vitamin C Improves the Inhibitory Effects of Oxaliplatin on HCT-116 Colorectal Cancer Growth and Progression Through Cellular Oxidant Function-associated Cadherin Molecules
Anticancer Research / October 2023
- Increased platelet activation and lower platelet-monocyte aggregates in COVID-19 patients with severe pneumonia
PLoS ONE / March 2023
- Riceberry Rice Germination and UVB Radiation Enhance Protocatechuic Acid and Vanillic Acid to Reduce Cellular Oxidative Stress and Suppress B16F10 Melanogenesis Relating to F-Actin Rearrangement
Plants / February 2023
- Role of Oxidative Stress-Dependent C/EBPβ Expression on CAF Transformation Inducing HCT116 Colorectal Cancer Cell Progression; Migration and Invasion
Asian Pacific Journal of Cancer Prevention / 2023
- Anticancer and Antimutagenic Properties of Pogonatherum paniceum on Colorectal Cancer Cells
World Journal of Oncology / 2023
- N-acetylcysteine improves the inhibitory effect of Quercetin-rich onion extract on HT-29 and HCT-116 colorectal cancer migration and invasion through iNOS suppression
International Journal of Medical Sciences / 2023
- Thioredoxin Reductase-1 as a Potential Biomarker in Fibroblast-Associated HCT116 Cancer Cell Progression and Dissemination in a Zebrafish Model
Cancers / January 2023
- Aqueous Thunbergia laurifolia leaf extract alleviates paraquat-induced lung injury in rats by inhibiting oxidative stress and inflammation
BMC Complementary Medicine and Therapies / December 2022
- YAP, a novel target regulates F-actin rearrangement-associated CAFs transformation and promotes colorectal cancer cell progression
Biomedicine and Pharmacotherapy / November 2022
- Green Curmin Reduces Pro-inflammatory Cytokines and Fibroblast-Associated Colon Cancer Migration
Pharmaceutical Sciences / December 2021
- Quercetin inhibits colorectal cancer cells induced-angiogenesis in both colorectal cancer cell and endothelial cell through downregulation of vegf-a/vegfr2
Scientia Pharmaceutica / June 2021
- Onion peel extract inhibits cancer cell growth and progression through the roles of L1CAM, NF-κB, and angiogenesis in HT-29 colorectal cancer cells
Preventive Nutrition and Food Science / 2021
- Modified Riceberry rice extract suppresses melanogenesis-associated cell differentiation through tyrosinase-mediated MITF downregulation on B16 cells and in vivo zebrafish embryos
Research in Pharmaceutical Sciences / October 2020
- Additive effect of a combination of artocarpus lakoocha and glycyrrhiza glabra extracts on tyrosinase inhibition in melanoma B16 cells
Pharmaceuticals / October 2020
- Germinated riceberry rice enhanced protocatechuic acid and vanillic acid to suppress melanogenesis through cellular oxidant-related tyrosinase activity in B16 cells
Antioxidants / March 2020
- Liposomes Encapsulating Artocarpus lakoocha Roxb. and Glycyrrhiza glabra L. Extracts: Characterization and Shelf Life of Freeze-Dried Vesicles
Journal of Food Health and Bioenvironmental Science / January - April 2020
- Study on effect of inductively coupled ar/o2 plasma in e-and h-mode on riceberry rice by sem/eds
Solid State Phenomena / 2020
- Oxyresveratrol inhibits cellular tyrosinase-related oxidative stress-induced melanogenesis in B16 melanoma cells
Journal of Applied Pharmaceutical Science / 2020
- Erratum: Effect of aqueous leaf extract of Thunbergia laurifolia on alcohol-induced liver injury in rats (Palipoch et al Trop J Pharm Res, (2019) 18, 4, (823-828), 10.4314/tjpr.v18i4.20)
Tropical Journal of Pharmaceutical Research / May 2019
- Association of XPO1 overexpression with NF-κB and Ki67 in colorectal cancer
Asian Pacific Journal of Cancer Prevention / 2019
Oral Presentations
- Pornnapat Chusangnin, Witchuda Payuhakrit, Achiraya Thammasakchai, Prasit Suwannalert. Unpolished Thai rice Induced Pro-Oxidants and Cellular Apoptosis in HT-29 Colorectal Cancer Cells. Mah Fah Luang University International Conference. Chaing rai, Thailand 2016 (p. 18-24).
- Tharathip Muangthong, Witchuda Payuhakrit, Prasit Suwannalert. Unpolished Thai rice induce cancer cell toxicity and suppressed cellular oxidants-related to cancer cell migration in Caco-2 cells. Mah Fah Luang University International Conference. Chaing rai, Thailand 2016 (p.11-17).
- Pitchaya Kornmai, Teerapat Rodboon, Prasit Suwannalert. The inhibitory effects of riceberry on cellular oxidants and melanogenesis in B16 melanoma cells. Mah Fah Luang University International Conference. Chaing rai, Thailand 2016 (p.1-7).
- Achiraya Tammasakchai, Sareeya Reungpatthanaphong, Chaiyavat Chaiyasut, Suda Riengrojpitak, Prasit Suwannalert. The Effects of Unpolished Thai Rice on Aberrant Crypt Foci (ACF) Formation and Mucin Production in Azoxymethane (AOM)-Induced Colon Cancer. 7th Biennial Congress of ASEAN Society of Colorectal Surgeons, Singapore, Singapore 2014 (Oral Presentation).
- Prasit Suwannalert, Chaiyavat Chaiyasut, Sunee Chansakaow. Free Radicals Scavenging Ability and Oxidative Protein Damage Protection of Medicinal Plants in Thailand.The 3rd International Conference on Oxidative Stress in Skin Medicine and Biology. Andros, Greece 2006
- Prasit Suwannalert, Patcharee Boonsiri, Tueanjit Khampitak, Kovit Khampitak, Maitree Suttajit, Pote Sriboonlue, Puangrat Yongvanit. Tomatoes Intake Inversely Related to Cholesterol Levels in Northeastern Thai Elderly. The 11th Congress of Parenteral and Enteral Nutrition Society of Asia. Seoul, Korea. 2005
Poster Presentations
- Keerati Joyjamras, Sareeya Reungpatthanaphong, Achiraya Tammasakchai, Suda Riengrojpitak, Chaiyavat Chaiyasut, Prasit Suwannalert. High Phenolic Content of Unpolished Thai Rice Prevent Colorectal Aberrant Crypt Foci (ACF) Formation in Rats. 11th National Cancer Institute Conference, Bangkok, Thailand 2012.
- Achiraya Tammasakchai and Prasit Suwannalert. High Phenolics and Antioxidant Activity in Red Pigment Strain of Unpolished Thai Rice. 37th Congress of Science and Technology of Thailand, Bangkok, Thailand 2011 (Poster Presentation).
- Prasit Suwannalert, Sirichet Rattanachitthawat, Chaiyavat Chaiyasut, Suda Riengrojpitak. Oxidative Stress Preventionin Rats Consume Thai Brown Rice. CHE-USDC Congress II. Pattaya, Thailand 2009 (Poster Presentation).
- Prasit Suwannalert, Patcharee Boonsiri, Tueanjit Khampitak, Kovit Khampitak, Pote Sriboonlue, Puangrat Yongvanit, Maitree Suttajit. Tomato, lycopene may play an important balance role between oxidative stress and antioxidant capacity in Thais people. The International Free Radical Summer School 2006. Spetses Island, Greece 2006 .
- Prasit Suwannalert, Patcharee Boonsiri, Tueanjit Khampitak, Kovit Khampitak, Pote Sriboonlue, Puangrat Yongvanit. The Levels of Lycopene, Alpha-tocopherol and a Marker of Oxidative Stress in Healthy Northeast Thai Elderly. The joint 8th IUNS-International Symposium on Clinical Nutrition (8th ISCN) and 5th Asia-Pacific Clinical Nutrition Society (5th APCNS) Conference 2006, Hangzhou, China.
- Prasit Suwannalert, Patcharee Boonsiri, Tueanjit Khampitak, Kovit Khampitak, Pote Sriboonlue, Puangrat Yongvanit. Serum Lycopene Level in Khon Kaen Healthy Elders. The 1st International Conference on Natural Products for Health and Beauty. Mahasarakham, Thailand. 2005
