Research Topic
Anti-oxidants and Innovative Natural Products
Oxidative stress is an imbalance between free radicals and anti-oxidant capacity. It has been proposed to play an important role in the progression of pathological changes including cancer, aging, and hyperpigmentation.
We emphasize on the research field of innovative natural products to prevent pathological changes of cancer, aging, and hyperpigmentation.
- Scopes of the research:
– Innovative Natural Products
– Free radicals and Anti-oxidants
– Oxidative Stress and Patho-mechanisms; Cancer, Aging, Hyperpigmentation
Prasit Suwannalert, Ph.D
Dean, Associate Professor
Witchuda Payuhakrit, Ph.D
Assistant Professor
Research Topic
Natural products and cancer treatment
The research focus on using natural products which involved the use of phytochemicals and even whole plan extracts to prevent, combat or reverse the processes of cellular and molecular in carcinogenesis as a chemopreventive treatment to inhibit cancers. Current research topics mostly emphasized on how natural products can modulate inflammatory pathways and thus affect the survival, proliferation, invasion, angiogenesis and reverse the chemotherapeutic resistance of the cancer.
- Scopes of the research:
– Tumor microenvironment
– Natural products and cancer treatment
– Natural products and aging prevention
Research Topic
Hypoxia and cancer biology
Cancer microenvironment plays a crucial role in progression, aggressiveness and resistance to treatment in many types of cancer. Specifically, hypoxic microenvironment (low oxygenation) due to fast tumor growth exceeding rate of new blood vessel formation can activate various molecular pathways involved with carcinogenesis and drug resistance. Our laboratory aims to study various responses to hypoxic activation and the molecular pathways involved to ultimately develop novel treatment strategies for cancer.
- Scopes of the research:
– Hypoxia-induced drug resistance
– Hypoxia-induced microparticles
– Hypoxia-induced cancer stem cells
Titipatima Sakulterdkiat, M.D., Ph.D
Lecturer
Chonnapat Naktubtim
Assistant Instructor
Research Topic
Inflammation and Cancer
Inflammation can contribute to cancer development and progression through dysregulation of various signaling pathways, promoting the expression of genes involved in cell survival, proliferation, angiogenesis, and resistance to apoptosis. Our research aims to understand the biology of inflammation-associated cancers which is crucial for developing targeted therapeutic approaches. Additionally, identifying biomarkers associated with inflammation and cancer can aid in early detection, prognosis, and monitoring of treatment response in patients.
Research Topic
Photobiology and skin aging
The ultraviolet (UV) exposure leads skin problems, such as wrinkles, hyperpigmentation and skin cancer.
My relevant areas of interest are about the biological responses of skin associated with photobiological field through the mechanisms in both in vitro and in vivo including the investigation of the bioactive compounds extracted from natural products to protect against photoaging.
- Scopes of the research:
– Photobiology
– Skin aging
– Melanongenesis
– Natural extracts
Nisamanee Charoenchon, Ph.D
Lecturer